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Prescribing Information Indication Patient Site
Patient Support and Savings

Financial Assistance

Additional Support

Financial assistance

Eligible patients pay as little as $5 for their monthly copay

Eligibility required. Annual savings up to $20,000. State and Federal Beneficiaries not eligible. Offer not valid for cash-paying patients. Terms and conditions apply, see below for full details.

To learn more about patient support available for SOMAVERT, call
1-800-645-1280

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TERMS AND CONDITIONS

By using this copay card, you acknowledge that you currently meet the eligibility criteria and will comply with the terms and conditions described below:

  • Patients are not eligible to use this card if they are enrolled in a state or federally funded insurance program, including but not limited to Medicare, Medicaid, TRICARE, Veteran Affairs health care, a state prescription drug assistance program, or the Government Health Insurance Plan available in Puerto Rico (formerly known as “La Reforma de Salud”).
  • Patient must have private insurance. Offer is not valid for cash-paying patients. Patients are responsible for as little as a $5 monthly copayment based upon program utilization. The value of this Copay Card is limited to a maximum of $20,000 per calendar year.
  • This copay card is not valid when the entire cost of your prescription drug is eligible to be reimbursed by your private insurance plan or other private health or pharmacy benefit programs.
  • You must deduct the value of this copay card from any reimbursement request submitted to your private insurance plan, either directly by you or on your behalf.
  • You are responsible for reporting use of the copay card to any private insurer, health plan, or other third party who pays for or reimburses any part of the prescription filled using the copay card, as may be required. You should not use the copay card if your insurer or health plan prohibits use of manufacturer copay cards.
  • You must be 18 years of age or older to redeem the copay card.
  • This copay card is not valid where prohibited by law.
  • Copay card cannot be combined with any other savings, free trial or similar offer for the specified prescription.
  • Copay card will be accepted only at participating pharmacies.
  • If your pharmacy does not participate, you may be able to submit a request for a rebate in connection with this offer.
  • This copay card is not health insurance.
  • Offer good only in the U.S. and Puerto Rico.
  • Copay card is limited to 1 per person during this offering period and is not transferable.
  • A copay card may not be redeemed more than once per 30 days per patient.
  • No other purchase is necessary.
  • No membership fee.
  • Data related to your redemption of the copay card may be collected, analyzed, and shared with Pfizer, for market research and other purposes related to assessing Pfizer’s programs. Data shared with Pfizer will be aggregated and de-identified; it will be combined with data related to other copay card redemptions and will not identify you.
  • Pfizer reserves the right to rescind, revoke or amend this offer without notice.
  • Offer expires 12/31/2023.

For more information, visit our website www.somavert.com, call 1-800-645-1280 or visit Pfizer.com. SOMAVERT Copay Support Program, PO Box 220746, Charlotte, NC 28222-0746

SOMAVERT support for your patientsCost and coverage support is available for eligible patients taking SOMAVERT through the Pfizer Bridge Program®
  • Dedicated PCC support:
    • The Pfizer Bridge Program* assigns a dedicated Patient Care Consultant (PCC) to assist with insurance coverage and provide your patients with reimbursement support throughout therapy
    • Each PCC is knowledgeable about regional payers and individual plans and can help research coverage for your SOMAVERT patients when their insurance changes
  • Patient Assistance Program: Provides qualifying uninsured and government insured patients with SOMAVERT at no cost
  • Self-injection training: Patients can get one-on-one, virtual or in-home training by qualified nurses. To request training for your patient during enrollment, check the "Patient Injection Training Requested" box on the SOMAVERT Patient Enrollment Form
Certain programs and services powered by Pfizer RxPathways®.Eligible patients must meet financial qualifications and also be diagnosed with an FDA-approved indication for SOMAVERT. They must be residents of the United States or Puerto Rico who are treated by physicians and must have a completed Patient Assistance Program application and Patient Authorization Form. Some exclusions may apply. Pfizer reserves the right to rescind, revoke, or amend this offer without notice.Updated Pfizer Bridge Program provider portal Discover the support programs available to your patients The updated Pfizer Bridge Program provider portal offers the following features:
  • Help patients enroll in the Pfizer Bridge Program 
  • Conduct electronic Benefits Verifications
  • Prepare and submit electronic Prior Authorization requests 
  • Provide e-signatures for SOMAVERT prescriptions 
  • Track patient's status and receive notifications 
  • Access digital forms and resources 
References:Trainer PJ, Drake WM, Katznelson L, et al. Treatment of acromegaly with the growth hormone–receptor antagonist pegvisomant. N Engl J Med. 2000;342(16):1171-1177.SOMAVERT. Prescribing information. Pfizer Inc.; 2021.Katznelson L, Laws ER Jr, Melmed S, et al. Acromegaly: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2014;99(11):3933-3951.Data on file. Pfizer Inc., New York, NY.Barkan AL, Burman P, Clemmons DR, et al. Glucose homeostasis and safety in patients with acromegaly converted from long-acting octreotide to pegvisomant. J Clin Endocrinol Metab. 2005;90(10):5684-5691.Melmed S, Colao A, Barkan M, et al. Guidelines for acromegaly management: an update. J Clin Endocrinol Metab. 2009;94(5):1509-1517.Herman-Bonert VS, Zib K, Scarlett JA, Melmed S. Growth hormone receptor antagonist therapy in acromegalic patients resistant to somatostatin analogs. J Clin Endocrinol Metab. 2000;85(8):2958-2961.Melmed S. Acromegaly. N Engl J Med. 1990;322(14):966-977.Kopchick JJ. Discovery and mechanism of action of pegvisomant. Eur J Endocrinol. 2003;148(suppl 2):S21-S25.van der Lely AJ, Hutson RK, Trainer PJ, et al. Long-term treatment of acromegaly with pegvisomant, a growth hormone receptor antagonist. Lancet. 2001;358(9295):1754-1759.Parkinson C, Drake WM, Roberts ME, Meeran K, Besser GM, Trainer PJ. A comparison of the effects of pegvisomant and octreotide on glucose, insulin, gastrin, cholecystokinin, and pancreatic polypeptide responses to oral glucose and a standard mixed meal. J Clin Endocrinol Metab. 2002;87(4):1797-1804.Freda PU, Gordon MB, Kelepouris N, Jonsson P, Koltowska-Haggstrom M, van der Lely AJ. Long-term treatment with pegvisomant as monotherapy in patients with acromegaly: experience from ACROSTUDY. Endocr Pract. 2015;21(3):264-274.Fleseriu M, Führer-Sakel D, van der Lely AJ, et al. More than a decade of real-world experience of pegvisomant for acromegaly: ACROSTUDY. Eur J Endocrinol. 2021;185(4):525-538.
Support and Services Connect eligible patients to support services Download form Loading Injection training video gives step-by-step instructions for use View now Loading

To report an adverse event, please call 1-800-438-1985

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PP-MCL-USA-0367
INDICATION SOMAVERT® (pegvisomant for injection) is indicated for the treatment of acromegaly in patients who have had an inadequate response to surgery or radiation therapy, or for whom these therapies are not appropriate. The goal of treatment is to normalize serum insulin-like growth factor-I (IGF-I) levels.

Please see full Prescribing Information.
Important Safety Information

Patients on opioids often needed higher serum pegvisomant concentrations to achieve appropriate IGF-I suppression compared with patients not receiving opioids.

Patients with acromegaly and diabetes mellitus being treated with insulin and/or oral hypoglycemic agents may require dose reductions of these therapeutic agents after the initiation of treatment with SOMAVERT.

Important safety information regarding liver test monitoring

Baseline serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), serum total bilirubin (TBIL), and alkaline phosphatase (ALP) levels should be obtained prior to initiating therapy with SOMAVERT. Monitor liver tests based on baseline values and changes during therapy according to the schedule in the full Prescribing Information.

Asymptomatic, transient elevations in transaminases up to 15 times ULN have been observed in <2% of subjects among two open-label trials (with a total of 147 patients). These reports were not associated with an increase in bilirubin. Transaminase elevations normalized with time, most often after suspending treatment. Postmarketing reports have identified elevations in serum hepatic transaminases up to >20 times ULN associated with elevation in total bilirubin >2 times ULN. In many of these cases, discontinuation of SOMAVERT therapy resulted in improvement or resolution of hepatic laboratory abnormalities. If a patient develops liver test elevations, or any other symptoms of liver dysfunction while receiving SOMAVERT, please see Liver Tests section of the full Prescribing Information.

In subjects with systemic hypersensitivity reactions, caution and close monitoring should be exercised when reinitiating SOMAVERT therapy.

The most common adverse events (>6% and at frequencies greater than placebo) in the active treatment arms in a placebo-controlled study (N=112) included infection (23%), pain (14%), nausea (14%), diarrhea (14%), abnormal liver function tests (12%), flu syndrome (12%), and injection-site reaction (11%).

Lipohypertrophy has been reported in patients treated with SOMAVERT; therefore, injection sites should be rotated daily.

Indication

SOMAVERT® (pegvisomant for injection) is indicated for the treatment of acromegaly in patients who have had an inadequate response to surgery or radiation therapy, or for whom these therapies are not appropriate. The goal of treatment is to normalize serum insulin-like growth factor-I (IGF-I) levels.
 

Please see full Prescribing Information.